| dc.contributor.author | Oketch-Rabah, HA | |
| dc.contributor.author | Christensen, SB | |
| dc.contributor.author | Frydenvang,K | |
| dc.contributor.author | Dossaji, SF | |
| dc.contributor.author | Theander, TG | |
| dc.contributor.author | Cornett, C | |
| dc.contributor.author | Watkins, WM | |
| dc.contributor.author | Kharazmi, A | |
| dc.contributor.author | Lemmich, E | |
| dc.date.accessioned | 2013-06-19T15:46:08Z | |
| dc.date.available | 2013-06-19T15:46:08Z | |
| dc.date.issued | 1998 | |
| dc.identifier.citation | H. A. Oketch-Rabah, S. Brøgger Christensen, Karla Frydenvang et al (1998). Antiprotozoal Properties of 16, 17-Dihydroxybrachycalyxolide from Vernonia brachycalyx. Planta Med 1998; 64(6): 559-562 | en |
| dc.identifier.uri | https://www.thieme-connect.com/ejournals/abstract/10.1055/s-2006-957514 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/36441 | |
| dc.description.abstract | Extracts of the leaves from Vernonia brachycalyx showed in vitro activity against Plasmodium falciparum and promastigotes of Leishmania major. The germacrane dilactone 16,17-dihydrobrachycalyxolide (1) which was previously isolated from the aerial parts of the plant was shown to be the major antiplasmodial principle. An X-ray crystallographic analysis established the absolute configuration and some signals in the NMR spectra were reassigned. 16,17-Dihydrobrachycalyxolide (1) elicited a strong antiplasmodial and antileishmanial activity but also a high toxicity against human lymphocytes. | en |
| dc.language.iso | en | en |
| dc.title | Antiprotozoal Properties of 16, 17-Dihydroxybrachycalyxolide from Vernonia brachycalyx | en |
| dc.type | Article | en |
