| dc.contributor.author | Makanya, AN | |
| dc.contributor.author | Koller, T | |
| dc.contributor.author | Hlushchuk, R | |
| dc.contributor.author | Djonov, V | |
| dc.date.accessioned | 2013-06-25T14:17:51Z | |
| dc.date.available | 2013-06-25T14:17:51Z | |
| dc.date.issued | 2012 | |
| dc.identifier.citation | Makanya AN, Koller T, Hlushchuk R, Djonov V.,Pre-hatch lung development in the ostrich,Respir Physiol Neurobiol. 2012 Mar 15;180(2-3):183-92 | en |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/22138612 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/39864 | |
| dc.description.abstract | We studied development of the ostrich lung using light microscopy as well as electron microscopy techniques. At E24, the lung comprised a few epithelial tubes, interspersed with abundant mesenchyme with scattered profiles of incipient blood vessels. Between E24 and E39, the epithelial thickness was reduced by 90% from 13.5 ± 0.41 μm to 1.33 ± 0.014 μm (mean ± SD, respectively). Atria were evident at E32, and by E35, the first portions of the blood-gas barrier (BGB) measuring 3.41 ± 1.12 μm were encountered. Gas exchange tissue was well formed by E39 with atria, infundibulae, air capillaries and a mature blood-gas barrier (BGB). BGB formation proceeded through the complex processes of secarecytosis and peremerecytosis, which entailed decapitation of epithelial cells by cutting or pinching off respectively and by E39, the BGB was thin at 2.21 ± 1.21 μm. Vascular remodeling by intussusceptive angiogenesis was a late stage process mediated by intraluminal pillars in the pulmonary vasculature | en |
| dc.language.iso | en | en |
| dc.publisher | University of Nairobi, | en |
| dc.title | Pre-hatch lung development in the ostrich. | en |
| dc.type | Article | en |
| local.publisher | Department of Veterinary Anatomy & Physiology, | en |
