dc.contributor.author | Nyamogoba, HD | |
dc.contributor.author | Mbuthia, G | |
dc.contributor.author | Mining, S | |
dc.contributor.author | Kikuvi, G | |
dc.contributor.author | Biegon, R | |
dc.contributor.author | Mpoke, S | |
dc.contributor.author | Menya, D | |
dc.contributor.author | Waiyaki, PG | |
dc.date.accessioned | 2013-06-25T14:52:13Z | |
dc.date.available | 2013-06-25T14:52:13Z | |
dc.date.issued | 2012-09 | |
dc.identifier.citation | Afr Health Sci. 2012 Sep;12(3):305-11. | en |
dc.identifier.uri | http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/23382744 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/39905 | |
dc.description.abstract | BACKGROUND:
Tuberculosis (TB) and HIV co-infections have a global prevalence with devastating morbidity and massive mortality, Sub-Saharan Africa being the worst hit.
OBJECTIVES:
To evaluate the prevalence of TB-HIV co-infection and demonstrate the confusion caused by NTM and HIV/AIDS co-infection in TB diagnosis and treatment in western Kenya.
METHODS:
In a cross-sectional study carried out at 10 hospitals in western Kenya, sputa from consenting 872 TB suspects underwent microscopy, and culture on Lowenstein-Jensen and Mycobacteria Growth Index Tube media. Isolates were identified using the Hain's GenoType(®) Mycobacterium CM and GenoType(®) Mycobacterium AS kits. A total of 695 participants were screened for HIV using Uni-Gold™ test and positives confirmed with the enzyme linked immunosorbent assay.
RESULTS:
A total of 346 (39.7%) participants were diagnosed with TB. Out of the 346 TB cases, 263 (76%) were tested for HIV infection and 110 (41.8%) of these were sero-positive (co-infected). The female to male TB-HIV co-infection prevalence ratio (PR) was 1.35. This study reports isolation of non-tuberculous mycobacteria from TB suspects at a rate of 1.7%.
CONCLUSION:
A high TB-HIV co-infection rate was observed in this study. The NTM disease could be misdiagnosed and treated as TB in western Kenya. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi. | en |
dc.subject | HIV co-infection | en |
dc.subject | TB diagnosis | en |
dc.subject | Tuberculosis | en |
dc.subject | high prevalence | en |
dc.title | HIV co-infection with tuberculous and non-tuberculous mycobacteria in western Kenya: challenges in the diagnosis and management. | en |
dc.type | Article | en |
local.publisher | Department of Public Health, Pharmacology and Toxicology | en |