Two-Year Results From a Multi-Site Randomized Trial of a Commercial Weight Loss Program
Date
2010Author
Cheryl, L. Rock
Shirley, W
Flatt, MS
La Jolla, CA
Karanja, n
Cynthia, Thomson
Nancy, E. Sherwood
Type
PresentationLanguage
enMetadata
Show full item recordAbstract
Commercial weight loss programs may contribute to efforts
to reduce the prevalence of obesity, although evidence of
efficacy and effects on metabolic and cardiovascular risk
factors is critical in evaluating the likelihood of sustained
benefits. The Jenny Craig (JC) program involves
individualized diet and exercise counseling (provided either
in-person at community-based sites or by telephone),
prepackaged foods and a low-energy density diet. The aims
of this study are (1) To test, in a multi-site randomized
controlled trial, whether the JC Centre-based and/or JC
Direct (telephone-based) interventions promote greater
weight loss and maintenance of that loss in overweight or
obese women over a 24-month period compared to usual
care (UC) conditions; and (2) To describe the effect of the
program (vs. UC conditions) on selected biochemical
factors, cardiopulmonary fitness, quality of life (QOL) and
eating attitudes and behaviors. At randomization,
participants (n=442) were 44(10) (mean[SD]) yrs, with BMI
33.8(3.4) kg/m2, weight 92.1(10.7) kg, and waist
circumference 108.6(9.6) cm. Two-year data are available
for 91% of study participants (n=406), and weight loss is -
8.1(8.6), -6.7(9.3), and -2.2(7.4) kg for the JC Centre-
based, JC Direct, and UC groups, an average weight
reduction of -8.7%, -7.3%, and -2.4% of initial weight,
respectively. The proportion of women at highest risk
(CRP>3 mg/L) in the JC arms decreased significantly from
53% at enrollment to 33% at two years, but was unchanged
in the UC arm. Interim analysis also shows the JC
intervention to promote favorable changes in lipid, leptin
and carotenoid levels, and improved cardiopulmonary fitness
URI
http://test141.jennycraig.com/assets/documents/corporate/claims/FAB-Poster_24Mo_TOS_10-10.pdfhttp://hdl.handle.net/11295/51177
Citation
Rock, C. L., RD, S. W. F., Karanja, N., & Pakiz, B. (2010, October). Two-Year Results From a Multi-Site Randomized Trial of a Commercial Weight Loss Program. In OBESITY (Vol. 18, pp. S99-S99). 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA: NATURE PUBLISHING GROUP.Publisher
University of Nairobi, college of agriculture and veterinary sciences,