Present status of in vitro cultivation of animal-infective African trypanosomes
Date
1980Author
Hirumi, H
Hirumi, K
Nelson, RT
Bwayo, JJ
Type
PresentationLanguage
en_USMetadata
Show full item recordAbstract
A detailed review is given of the cultivation of Trypanosoma brucei in vitro, especially at 37 deg C. Much information is given about technical procedures. By appropriately varying the culture conditions, especially the temperature, it has been possible to obtain the complete cyclic development of T. brucei in vitro in the presence of bovine feeder layer cells, suggesting that tsetse fly tissues are not necessary. During prolonged in vitro cultivation the trypanosomes tend to lose much of their virulence for mice. 38 references are cited.
URI
http://www.cabdirect.org/abstracts/19800870866.html;jsessionid=6E8B095E4D62886E0BF044C633D80350http://hdl.handle.net/11295/51433
Citation
UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases. : The in vitro cultivation of the pathogens of tropical diseases: Proceedings of the Workshop held in Nairobi, Kenya, 4-9 February 1979]. 1980 pp. 165-200Publisher
Department of Medical Microbiology, University of Nairobi