Some Further Fractions Of Arylacetic Acids And Related Compounds With Sodium Hypochlorite
Abstract
In the leactiol1 of arylacetic acids with alkaline sodium
hyp och Lorit e it has been shown t.hat the nature of the products
depends Oil the substit.uents on the ring. Hhen electron atlac-
ling groups arc present. the products arc the next. lower aldehyde
and/or carboxylic. acid: the type of product. being det.ermined
by the experirnen t aL cond i t i.ons , Whp.n electron releasing groups
are present the ring is activated towards substitution by
electrop~iJic chlorine to give ch10ro- and dichloro derivatives.
In phenylacetic acid itself, contrary to a previous report, we
have shown that both oxidat.ion/cleu:rhoxylation and chlorine
substitution of the ring pay take place.
PYlidyl acetic acids behave in a similar fashion t.o benze~e
deriva t ive s bearing e l ec t r on T",itbd~~±-ng groups.
Publisher
Department of Chemistry