dc.contributor.author | Muchira, JM | |
dc.contributor.author | Amugune, BK | |
dc.contributor.author | Ogeto, JO | |
dc.contributor.author | Thoithi, G N | |
dc.contributor.author | Kamau, J M | |
dc.date.accessioned | 2013-12-02T06:37:25Z | |
dc.date.available | 2013-12-02T06:37:25Z | |
dc.date.issued | 2013-06 | |
dc.identifier.citation | Muchira, JM, Amugune, BK,Ogeto, JO,Thoithi, G N,Kamau, J M ;june,2013.An Audit Of Hospital Radio-pharmacy Practice At Kenyatta National Hospital Nuclear Medicine Unit,presented at the 2nd International Scientific Conference, CHS And KNH, 19th - 21st June 2013. | en |
dc.identifier.uri | http://hdl.handle.net/11295/61345 | |
dc.description | An Audit Of Hospital Radio-pharmacy Practice At Kenyatta National Hospital Nuclear Medicine Unit,presented at the 2nd International Scientific Conference, CHS And KNH, 19th - 21st June 2013. | en |
dc.description.abstract | Radio-pharmacy or nuclear pharmacy is the specialty practice of pharmacy
which focuses on the safe and efficacious use of radiopharmaceuticals either
for diagnostic and therapeutic purposes. The practice combines the expertise of
pharmaceutical preparation and the skills needed to handle radioactive substances.
Although the use of radiopharmaceuticals has been growing worldwide, the
growth in developing countries has been slow with only Kenyatta National
Hospital and Aga Khan University Hospital offering radio-pharmacy services
in Kenya.
Diagnostic radiopharmaceuticals do not have major pharmacological effect
and their administration is not associated with major clinical side effects.
Their clinical use, however, is associated with a risk deriving from radiation
exposure and possible contamination during radiopharmaceutical formulation
by chemical, biological and microbiological impurities and thus quality control
of the radiopharmaceuticals is crucial.
Objective: The main objective of this research was to carry out an audit study on
radio pharmacy practice at Kenyatta National Hospital Nuclear Medicine Unit
in the Cancer Treatment Centre as per set international and regulatory standards.
The study was carried out using International Atomic Energy Agency (IAEA)
preformatted checklists and questionnaires for hospital radio-pharmacy practice
audits and the findings analyzed and evaluated using IAEA guidelines. Patient’s
treatment records were reviewed for radiopharmaceuticals use trends.
The facilities observed available included radioactivity monitoring meters
both for the working areas and the staff, functional hot lab, lead shielded waste
disposal containers and tank for radioactive materials. From 209 patients files
reviewed, it was observed that only three types of radiopharmaceuticals are used
in the hospital with Technetium 99mTc - MDP the most frequently used (51.2
%) followed by 131 I (47.8 %) and Technetium 99mTc-DTPA (1%). The
diagnostic uses were for bone scan (49 %), thyroid scan (25.5 %) and whole
bone scan (6.7%).
Other minor diagnostic uses (< 2 %) included thyroid ablation, renal scan, and
lung scan. 131I was the only one used for therapy (15.4 %) of thyrotoxicosis.
The practice of radio pharmacy at the Nuclear medicine unit has to a large
extent complied with the IAEA guidelines in the areas of administration,
procurement, staff training, standard operating procedures (SOPs), personnel
and environmental safety and waste disposal.
Inclusion of a pharmacist in the team should be considered to make it
multidisplinary and therefore more comprehensive in function.for input in
monitoring patient outcomes, set effective quality control / quality assurance
measures and initiate expansion of the range and use of radiopharmaceuticals
with better therapeutic outcomes to the patients. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi | en |
dc.title | An Audit Of Hospital Radio-pharmacy Practice At Kenyatta National Hospital Nuclear Medicine Unit | en |
dc.type | Presentation | en |
local.publisher | College of Health Sciences | en |