Kirkinine, a New Daphnane Orthoester with Potent Neurotrophic Activity from Synaptolepis kirkii

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Date
2000
Author
He, Weidong
Cik, Miroslav
Lesage, Anne
Van der Linden, Ilse
De Kimpe, Norbert
Appendino, Giovanni
Bracke, Johan
Mathenge, Simon G
Mudida, Francis P
Leysen, Josée E
Van Puyvelde, Luc
Type
Article
Language
en
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Abstract
The bioassay-guided fractionation of a dichloromethane extract from the roots of Synaptolepis kirkii using neuronal viability as a model allowed the isolation of the new daphnane orthoester kirkinine (1a) as a powerful neurotrophic constituent.
URI
http://pubs.acs.org/doi/abs/10.1021/np000249u
http://hdl.handle.net/11295/65712
Citation
J. Nat. Prod., 2000, 63 (9), pp 1185–1187
Publisher
University of Nairobi
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