dc.contributor.author | Ramasamy, R | |
dc.contributor.author | Kar, SK | |
dc.contributor.author | Jamnadas, H | |
dc.date.accessioned | 2014-04-24T13:18:51Z | |
dc.date.available | 2014-04-24T13:18:51Z | |
dc.date.issued | 1983-08 | |
dc.identifier.citation | International Journal for Parasitology Volume 13, Issue 4, August 1983, Pages 337–341 | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/pii/S002075198380037X | |
dc.identifier.uri | http://hdl.handle.net/11295/65969 | |
dc.description.abstract | Three strains of Leishmania donovani from America, India and Kenya and a strain of Leishmania mexicana were grown in culture as promastigotes. The parasites werw surface labelled by lactoperoxide-catalysed iodination and the surface proteins analysed by polyacrylamide gel electrophoresis and autoradiography. The four strains possessed surface proteins of similar mol.wts. including a 59,000 mol.wt. glycoprotein. Immune-precipitation using rabbit anti-Leishmania sera revealed that the 59,000 mol.wt. protein and other proteins on the surfaces of the promastigotes cross-reacted antigenically. Common surface antigens on the four strains was also shown by immunofluorescence studies using the rabbit anti-Leishmania sera and monoclonal antibodies raised against one of the strains. | en_US |
dc.language.iso | en | en_US |
dc.publisher | University of Nairobi | en_US |
dc.subject | Antigens; common antigens; electrophoresis; glycoprotein; kala-azar; Leishmania; leishmaniasis; monoclonal antibodies; surface antigens; surface proteins; vaccination | en_US |
dc.title | Cross-reacting Surface Antigens On Leishmania Promastigotes | en_US |
dc.type | Article | en_US |