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dc.contributor.authorRamasamy, R
dc.contributor.authorKar, SK
dc.contributor.authorJamnadas, H
dc.date.accessioned2014-04-24T13:18:51Z
dc.date.available2014-04-24T13:18:51Z
dc.date.issued1983-08
dc.identifier.citationInternational Journal for Parasitology Volume 13, Issue 4, August 1983, Pages 337–341en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S002075198380037X
dc.identifier.urihttp://hdl.handle.net/11295/65969
dc.description.abstractThree strains of Leishmania donovani from America, India and Kenya and a strain of Leishmania mexicana were grown in culture as promastigotes. The parasites werw surface labelled by lactoperoxide-catalysed iodination and the surface proteins analysed by polyacrylamide gel electrophoresis and autoradiography. The four strains possessed surface proteins of similar mol.wts. including a 59,000 mol.wt. glycoprotein. Immune-precipitation using rabbit anti-Leishmania sera revealed that the 59,000 mol.wt. protein and other proteins on the surfaces of the promastigotes cross-reacted antigenically. Common surface antigens on the four strains was also shown by immunofluorescence studies using the rabbit anti-Leishmania sera and monoclonal antibodies raised against one of the strains.en_US
dc.language.isoenen_US
dc.publisherUniversity of Nairobien_US
dc.subjectAntigens; common antigens; electrophoresis; glycoprotein; kala-azar; Leishmania; leishmaniasis; monoclonal antibodies; surface antigens; surface proteins; vaccinationen_US
dc.titleCross-reacting Surface Antigens On Leishmania Promastigotesen_US
dc.typeArticleen_US


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