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dc.contributor.authorShah, J
dc.contributor.authorRamasamy, R
dc.date.accessioned2014-04-24T13:22:22Z
dc.date.available2014-04-24T13:22:22Z
dc.date.issued1982-10
dc.identifier.citationInternational Journal for Parasitology Volume 12, Issue 5, October 1982, Pages 451–461en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/0020751982900765
dc.identifier.urihttp://hdl.handle.net/11295/65971
dc.description.abstractShah J. and Ramasamy R. 1982. Surface antigens on cercariae, schistosomula and adult worms of Schistosoma mansoni. International Journal for Parasitology12: 451–461. The surface protein antigens of Schistosoma mansoni were radiolabelled by lactoperoxidase catalysed I125-iodination and analysed by immune-precipitation and polyacrylamide gel electrophoresis. The results showed that regularly labelled surface antigens of mol. wts >150,000, 78,000, 45,000 and 22,000 were present on adult worms. Common surface antigens were observed on the cercariae, schistosomula and adult worms. It is suggested that surface antigens released from living adult worms can sensitise a host to react against the invading schistosomula of a secondary infection. However, the failure to vaccinate mice using material containing adult worm surface antigens suggests that the induction of protective immunity is a complex phenomenon.en_US
dc.language.isoenen_US
dc.publisherUniversity of Nairobien_US
dc.subjectAdult worms; Bolton-Hunter reagent; cercariae; concomitant immunity; electrophoresis; immunity to parasites; lactoperoxidase; membrane turnover; parasite surface; Schistosoma mansoni; schistosomiasis; schistosomula; surface antigens; surface iodination; surface proteins; trematodeen_US
dc.titleSurface Antigens On Cercariae, Schistosomula And Adult Worms Of Schistosoma Mansonien_US
dc.typeArticleen_US


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