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dc.contributor.authorNjagi, GDE
dc.contributor.authorGopalan, HNB
dc.date.accessioned2014-08-14T09:03:42Z
dc.date.available2014-08-14T09:03:42Z
dc.date.issued1982-11
dc.identifier.citationMutation Research/Genetic Toxicology Volume 102, Issue 3, October–November 1982, Pages 213–219en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/0165121882901318
dc.identifier.urihttp://hdl.handle.net/11295/73749
dc.description.abstractSodium sulphite and sodium benzoate induce in Vicia faba root meristems: (1) dose-dependent reduction in mitotic figures, (2) intact and severed anaphase bridges, (3) premature chromosome condensation heading to pycnofic nuclei, and (4) chromatin erosion in interphase nuclei. The effects are due to the anions and not due to the sodium ions. Complete recovery of mitotic figures and normal chromosome configurations were observed within the first 23–46 h of regrowth. Recovery was accompanied by severed anaphase bridges and micronuclei of various shapes. Both benzoate and sulphite inhibit DNA synthesis in Vicia faba root meristems. Sulphite was more effective than benzoate.en_US
dc.language.isoenen_US
dc.titleCytogenetic effects of the food preservatives — Sodium benzoate and sodium sulphite on Vicia faba root meristemsen_US
dc.typeArticleen_US
dc.type.materialenen_US


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