Browsing Journal Articles by Author "I, Igarashi"

Now showing items 1-1 of 1

    • Precursors of methotrexate target dihydrofolate reductase-thymidylate synthase of Babesia gibsoni 

      Aboge, G O; Terkawi, M; Goo, Y-K; Batbaatar, V; Nishikawa, Y; Sunaga, F; Namikawa, K; I, Igarashi; Fujisaki, K; Suzuki, H; Xuan, X (Department of Public Health Pharmacology and Toxicology, 2010)
      It is not known whether precursors of methotrexate, such as 2, 4-diamino-6-hydroxymethyl-pteridine (DAP) and 2, 4-diamino-N10-methyl-pteroic acid (DAMPA), could target the dihydrofolate reductase-thymidylate synthase ...