Browsing Journal Articles by Subject "Babesia gibsoni"
Now showing items 1-6 of 6
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Babesia gibsoni: Serodiagnosis of infection in dogs by an enzyme-linked immunosorbent assay with recombinant BgTRAP
(Department of Public Health Pharmacology and Toxicology, 2008)The thrombospondin-related adhesive protein of Babesia gibsoni (BgTRAPJ is known as an immunodominant antigen and is, there¬fore, considered as a candidate for the developmentof a diagnostic reagent for canine babesiosis. ... -
Cloning, Expression, and Characterization of Babesia gibsoni Dihydrofolate Reductase-Thymidylate Synthase: Inhibitory Effect of Antifolates on Its Catalytic Activity and Parasite Proliferation
(Department of Public Health Pharmacology and Toxicology, 2008)Dihydrofolate reductase-thymidylate synthase (DHFR-TS) is a well-validated antifolate drug target in certain pathogenic apicomplexans, but not in the genus Babesia, including Babesia gibsoni. Therefore, we isolated, cloned, ... -
Identification of a novel B. gibsoni 27-kDa protein as a serodiagnostic antigen
(Department of Public Health, Pharmacology & Toxicology, University of Nairobi, 2008)A novel gene encoding 27-kDa protein was identified by the screening of Babesia gibsoni cDNA library with acutely infected dog serum. The BgP27 is a single copy gene with a predicted open reading frame of 762 bp and 254 ... -
Identification of Secreted Antigen 3 from Babesia gibsoni
(Department of Public Health, Pharmacology and Toxicology, 2009)A cDNA expression library of Babesia gibsoni was screened with the serum collected from a dog experimentally infected with B. gibsoni. A novel antigen sharing homology with secreted antigen 1 of B. gibsoni was isolated. ... -
Molecular and immunological characterization of Babesia gibsoni
(Department of Public Health, Pharmacology and Toxicology, 2009)Serological immune screening was used to identify a gene encoding heat shock protein-70 from Babesia gibsoni (BgHSP-70) that showed high homology with HSP-70s from other apicomplexan parasites. This gene corresponded to a ... -
Molecularand immunological characterization of Babesia gibsoni and Babesia microti heat shockprotein-70
(Department of Public Health Pharmacology and Toxicology, 2009)Serological immunoscreening was used to identify a gene encoding heat shock protein-70 from Babesia gibsoni (BgHSP-70) that showed high homology with HSP-70s from other apicomplexan parasites. This gene corresponded to ...