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Sustained changes in sexual behavior by female sex workers after completion of a randomized HIV prevention trial
(2007)
INTRODUCTION:
Behavioral interventions in female sex workers (FSWs) are associated with changes in sexual behavior and reduced rates of sexually transmitted infections (STIs) and HIV We examined the sustainability of ...
HIV-1 infection alters the retinol-binding protein:transthyretin ratio even in the absence of the acute phase response.
(University of Nairobi,, 2005)
he ratio of retinol-binding protein (RBP) to transthyretin (TTR) has been proposed as an indirect method with which to assess vitamin A status in the context of inflammation. Few studies have been conducted among adults, ...
Role of Sexually Transmitted Infections in Accelerated HIV-1 Disease Progression
(University of nairobi, 2000)
HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers.
(University of Nairobi,, 2008-03)
OBJECTIVES:
HIV-neutralizing immunoglobulin A (IgA) and HIV-specific cellular immunity have been described in highly exposed, persistently seronegative (HEPS) individuals, but well controlled studies have not been performed. ...
Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection.
(, 2000-05)
Certain human leukocyte antigens, by presenting conserved immunogenic epitopes for T cell recognition, may, in part, account for the observed differences in human immunodeficiency virus type 1 (HIV-1) susceptibility. To ...
Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses
(University of Nairobi, 2001-02-01)
Resistance to HIV infection in a small group of Kenyan sex workers is associated with CD8+-lymphocyte responses to HIV cytotoxic T-lymphocyte (CTL) epitopes. Eleven prostitutes meeting criteria for HIV resistance seroconverted ...
HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi
(, 2000)
Understanding how individuals with a high degree of HIV exposure avoid persistent infection is paramount to HIV vaccine design. Evidence suggests that mucosal immunity, particularly virus-specific CTL, could be critically ...
Evaluation of a low- dose nonoxynol-9 gel for the prevention of sexually transmitted diseases: a randomised clinical trial, Sex Transm Dis 2001
(University of Nairobi, 2001)
Objective: To assess the relation between selenium deficiency and vaginal or cervical shedding of HIV-1-infected cells. Design: Cross-sectional study of 318 HIV-1 seropositive women in Mombasa, Kenya. Methods: Vaginal and ...
Lymphocyte Subsets In Human Immunodeficiency Virus Type 1-infected And Uninfected Children In Nairobi.
(University of Nairobi, 2001-05-20)
Background: Reference lymphocyte subset values for African children are lacking. This study documents these values as well as their alterations associated with perinatal and postnatal HIV-1 transmission and with protection ...