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The role of drought among agro-pastoral communities in a semi-arid environment: The case of Botswana
(University of Nairobi, 2013-04)
Agro-pastoral livelihoods in semi-arid Botswana have evolved and adapted to recurrent droughts endemic to the region. Droughts, more than any other phenomena, have shaped and influenced rural communities' interaction with ...
The Discovery of GS-9669, a Thumb Site II Non-nucleoside Inhibitor of NS5B for the Treatment of Genotype 1 Chronic Hepatitis C Infection
(University of Nairobi, 2013-11-06)
Investigation of thiophene-2-carboxylic acid HCV NS5B site II inhibitors, guided by measurement of cell culture medium binding, revealed the structure-activity relationships for intrinsic cellular potency. The pharmacokinetic ...
A comparative investigation of methods for longitudinal data with limits of detection through a case study
(2012-04)
The statistical analysis of continuous longitudinal data may be complicated since quantitative levels of bioassay cannot always be determined. Values beyond the limits of detection (LOD) in the assays may not be observed ...
Nutrients and antinutrients composition of raw, cooked and sun-dried sweet potato leaves
(2011)
Traditional indigenous vegetables are the most economically efficient source of micronutrients in terms of both land required and production costs per unit. Promotion of production and consumption of such micronutrient-rich ...
Antiplasmodial activity of compounds from the surface exudates of Senecio roseiflorus
(University of Nairobi, 2013-02)
From the surface exudates of Senecio roseiflorus fourteen known methylated flavonoids and one phenol were isolated and characterized. The structures of these compounds were determined on the basis of their spectroscopic ...
Quality of hospital care for sick newborns and severely malnourished children in Kenya: A two-year descriptive study in 8 hospitals.
(2011-11-11)
Background
Given the high mortality associated with neonatal illnesses and severe malnutrition and the development of packages of interventions that provide similar challenges for service delivery mechanisms we set out ...
Effect of Amaranthus hybridus on the immunity of laboratory white albino rats
(2013)
This study determined the role of A. hybrids in boosting the immunity of female albino rats in the laboratory. They were
randomly assigned to four groups, A to D and followed for 16 weeks during which groups A to C had ...
Challenges for consent and community engagement in the conduct of cluster randomized trial among school children in low income settings: experiences from Kenya.
(University of Nairobi, 2013)
BACKGROUND:
There are a number of practical and ethical issues raised in school-based health research, particularly those related to obtaining consent from parents and assent from children. One approach to developing, ...
Safety and Immunogenicity Study of Multiclade HIV-1 Adenoviral Vector Vaccine Alone or as Boost following a Multiclade HIV-1 DNA Vaccine in Africa
(University of nairobi, 2010)
Abstract
BACKGROUND:
We conducted a double-blind, randomized, placebo-controlled Phase I study of a recombinant replication-defective adenovirus type 5 (rAd5) vector expressing HIV-1 Gag and Pol from subtype B and Env ...
Mortality Projection: Curve Fitting And Linear Regression
(2011)
This study was aimed at predicting future mortality rates given two main scenarios. The first is in the
case where there is a body of mortality tables from the past and the second is in the case where such a
database ...