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Anti-inflammatory Flavanones and Flavones from Tephrosia linearis
(ACS, 2020-03-10)
Phytochemical analysis of a methanol–dichloromethane (1:1) extract of the aerial parts of Tephrosialinearis led to the isolation of 18 compounds. Seven of these, namely, lineaflavones A–D (1–4), 6-methoxygeraldone (5), ...
Diversity and function of maternal hiv-1-specific antibodies at the time of vertical transmission
(UoN, 2020)
Infants of HIV-positive mothers can acquire HIV infection by various routes, but even in the absence of antiviral treatment, the majority of these infants do not become infected. There is evidence that maternal antibodies ...
First detection of Theileria parva in cattle from Cameroon in the absence of the main tick vector Rhipicephalus appendiculatus
(University of Nairobi, 2020)
A major risk factor for the spread of livestock diseases and their vectors is the uncontrolled transboundary movement of live animals for trade and grazing. Such movements constrain effective control of tick-transmitted ...
A review of recent research on Theileria parva: Implications for the infection and treatment vaccination method for control of East Coast fever
(University of Nairobi, 2020)
The infection and treatment (ITM) live vaccination method for control of Theileria parva infection in cattle is increasingly being adopted, particularly in Maasai pastoralist systems. Several studies indicate positive ...
Anti-inflammatory norhopanes from the root bark of Fagaropsis angolensis (Engl.) H.M.Gardner
(University of Nairobi, 2020)
Two new norhopane derivatives namely 3β,6β,22-trihydroxy-7β,11α-di[(4-hydroxybenzoyl)oxy]-21αH-24-norhopa-4(23)-ene (1) and 3β,6β,22-trihydroxy-7β-[(4-hydroxybenzoyl)oxy]-21αH-24-norhopa-4(23)-ene (2) together with two ...
Multidisciplinary approach towards training of the next generation of forensic DNA analysts in Africa; a Kenyan perspective
(University of Nairobi, 2020)
The uptake of forensic DNA testing technologies in Africa has been slow despite the revolutionary technology being discovered and adopted 3 decades ago. African governments and partners have invested in construction and ...
Diversity and Multiplicity of P. falciparum infections among asymptomatic school children in Mbita, Western Kenya
(University of Nairobi, 2020)
Multiplicity of infection (MOI) and genetic diversity of P. falciparum infections are important surrogate indicators for assessing malaria transmission intensity in different regions of endemicity. Determination of MOI and ...
Biopsychosocial risk factors and knowledge of cervical cancer among young women: A case study from Kenya to inform HPV prevention in Sub-Saharan Africa
(University of Nairobi, 2020)
Background: Cervical cancer is the second most common female reproductive cancer after breast cancer with 84% of the cases in developing countries. A high uptake of human papilloma virus (HPV) vaccination and screening, ...
Movement reveals reproductive tactics in male elephants
(University of Nairobi, 2020)
Long-term bio-logging has the potential to reveal how movements, and hence life-history trade-offs, vary over a lifetime. Reproductive tactics in particular may vary as individuals' trade-off current investment versus ...
The role of alpha-synuclein as ferrireductase in neurodegeneration associated with Parkinson's disease
(University of Nairobi, 2020)
Misfolding of the protein α-synuclein contributes to the formation of the intracellular inclusion, Lewy bodies. Although these structures are not exclusive to Parkinson's disease, nevertheless, their presence in the ...