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Now showing items 11-20 of 20
Virus-encoded microRNA contributes to the molecular profile of EBV-positive burkitt lymphomas.
(University of Nairobi, 2015-07)
Burkitt lymphoma (BL) is an aggressive neoplasm characterized by consistent morphology and phenotype, typical clinical behavior and distinctive molecular profile. The latter is mostly driven by the MYC over-expression ...
Comparison of HIV 1 nef and gag Variations and Host HLA Characteristics as Determinants of Disease Progression among HIV1 Vertically Infected Kenyan Children.
(University of Nairobi, 2015-08)
OBJECTIVES:
Disease progression varies among HIV-1-infected individuals. The present study aimed to explore possible viral and host factors affecting disease progression in HIV-1-infected children.
METHODS:
Since ...
The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence.
(2015-09)
There are no commercially available vaccines against human protozoan parasitic diseases, despite the success of vaccination-induced long-term protection against infectious diseases. East Coast fever, caused by the protist ...
Genomic epidemiology of the current wave of artemisinin resistant malaria
(University of Nairobi, 2015)
Artemisinin resistant Plasmodium falciparum is advancing across Southeast Asia in a soft selective sweep involving at least 20 independent kelch13 mutations. In a large global survey, we find that kelch13 mutations which ...
New pneumococcal conjugate vaccine introductions in four sub-Saharan African countries: a cross-country analysis of health systems’ impacts
(University of Nairobi, 2015-09)
Background: Pneumonia is a main cause of under-five mortality in low-income settings. The pneumococcal conjugate vaccine (PCV) has been introduced in many countries as a tool in the disease’s prevention. Although PCV’s ...
Topic: Inguinal Hernia - Influence of guidelines on daily practice.
(University of Nairobi, 2015-04)
Antidiabetic and safety of lantana rhodesiensis in alloxan induced diabetic rats
(University of Nairobi, 2015)
Lantana rhodesiensis
Linn is used traditionally in the management of several diseases including diabetes mellitus;
however, its efficacy and safety is not scientifically evaluated. The aim of this study was to determine ...
Effectiveness of hormonal contraception in HIV-infected women using antiretroviral therapy.
(University of Nairobi, 2015)
OBJECTIVE:
The objective of this study is to assess whether antiretroviral therapy (ART) may diminish the effectiveness of hormonal contraceptive methods.
METHODS:
Using data from 5153 HIV-infected women followed ...
An insight into cervical cancer screening and treatment capacity in Sub Saharan Africa.
(University of Nairobi, 2015)
OBJECTIVE:
Approximately 85% of cervical cancer cases and deaths occur in resource-constrained countries where best practices for prevention, particularly for women with HIV infection, still need to be developed. The ...
Serologic evidence of the geographic distribution of bacterial zoonotic agents in Kenya, 2007.
(University of Nairobi, 2015-11-23)
Diseases of zoonotic origin contribute to the burden of febrile illnesses in developing countries. We evaluated serologic evidence of exposure to Bacillus anthracis, Brucella spp., spotted fever group rickettsioses (SFGR), ...