Search
Now showing items 11-20 of 1465
A comparative investigation of methods for longitudinal data with limits of detection through a case study
(2012-04)
The statistical analysis of continuous longitudinal data may be complicated since quantitative levels of bioassay cannot always be determined. Values beyond the limits of detection (LOD) in the assays may not be observed ...
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
(2012)
BACKGROUND:
Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The prognostic value of recently identified somatic mutations has not been systematically evaluated ...
How do novel molecular genetic markers influence treatment decisions in acute myeloid leukemia?
(2012)
Acute myeloid leukemia (AML) is the most common acute leukemia diagnosed in adults, and the majority of patients with AML die from relapsed disease. Although many studies over the past 4 decades have identified disease ...
Capturing Socio - Cultural Diversity and Chang e through Oral Literature.
(University of Nairobi, 2012)
Anthraquinones of the roots of Pentas micrantha
(University of Nairobi, 2012-12)
Pentas micrantha is used in the East African indigenous medicine to treat malaria. In the first investigation of this plant, the crude methanol root extract showed moderate antiplasmodial activity against the W2- (3.37 ...
Study on the microstructure of African wild silk cocoon shells and fibers
(2012-01)
Silk fibers and cocoon shells from four African wild silkmoths Gonometa postica, Anaphe panda, Argema mimosae and Epiphora bauhiniae-were studied to gain insight into the structure-property-function relations and potential ...
Steady rifting in northern Kenya inferred from deformed Holocene lake shorelines of the Suguta and Turkana basins.
(University of Nairobi, 2012-05-15)
A comparison of deformation rates in active rifts over different temporal scales may help to decipher variations in their structural evolution, controlling mechanisms, and evolution of sedimentary environments through time. ...
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression
(2012)
Recurrent somatic ASXL1 mutations occur in patients with myelodysplastic syndrome, myeloproliferative neoplasms, and acute myeloid leukemia, and are associated with adverse outcome. Despite the genetic and clinical data ...
Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes
(2012)
Experimental hyperlipidemia has shown to decrease cytochrome P450 3A4 and 2C11 expression and to increase liver concentrations and the plasma protein binding of halofantrine (HF) enantiomers. The present study examined the ...