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Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission.
(University of Nairobi, 2016)
BACKGROUND:
Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa. We hypothesized that a vaccine ...
Unblinded randomized control trial on prophylactic antibiotic use in gustilo II open tibia fractures at Kenyatta National Hospital, Kenya.
(University of Nairobi, 2016)
OBJECTIVE:
To determine the difference in infection rate between 24h versus five days of prophylactic antibiotic use in management of Gustilo II open tibia fractures.
DESIGN:
Unblinded randomized control ...
Identification and characterization of profilin antigen among Babesia species as a common vaccine candidate against babesiosis.
(University of Nairobi, 2016)
We have characterized a member of the profilin (PROF) family protein as a common antigen in three pathogens-Babesia bovis (B. bovis), Babesia bigemina (B. bigemina), and Babesia microti (B. microti)-and evaluated its ...
Variant Anatomy of the Nasal and Labial Branches of the Infraorbital Nerve.
(University of Nairobi, 2016)
Comprehensive understanding of the variations in the branches of the infraorbital nerve (ION) is vital to the prevention of iatrogenic nerve injury and successful ION blockade during orbitozygomatic facial procedures. Only ...
Dynamics of the developing chick Chorioallantoic membrane assessed by Stereology, allometry, Immunohistochemistry and molecular analysis.
(University of Nairobi, 2016)
The chick chorioallantoic membrane (CAM) is a widely used model for the study of angiogenesis, tumour growth, as well as drug efficacy. In spite of this, little is known about the developmental alteration from its appearance ...
Modeling the Cost-Effectiveness of Home-Based HIV Testing and Education (HOPE) for Pregnant Women and Their Male Partners in Nyanza Province, Kenya.
(University of Nairobi, 2016)
INTRODUCTION:
Women in sub-Saharan Africa face a 2-fold higher risk of HIV acquisition during pregnancy and postpartum and the majority do not know the HIV status of their male partner. Home-based couple HIV testing for ...
Esophageal squamous dysplasia is common in asymptomatic Kenyans: a prospective, community-based, cross-sectional study.
(University of Nairobi, 2016)
OBJECTIVES:
Esophageal squamous cell carcinoma (ESCC) is endemic in east Africa and is a leading cause of cancer death among Kenyans. The asymptomatic precursor lesion of ESCC is esophageal squamous dysplasia (ESD). We ...
Mapping international university partnerships identified by East African Universities as strengthening their medicine, nursing, and public health programs
(University of Nairobi, 2016)
Background
International university partnerships are recommended for increasing the capacity of sub-Saharan African universities. Many publications describe individual partnerships and projects, and tools are available ...
Changes in Vaginal Microbiota and Immune Mediators in HIV-1-Seronegative Kenyan Women Initiating Depot Medroxyprogesterone Acetate
(2016)
Background: Depot medroxyprogesterone acetate (DMPA) is associated with HIV acquisition. We studied changes in vaginal microbiota and inflammatory milieu after DMPA initiation.
Methods: In a cohort of HIV-negative Kenyan ...
Uptake and Effectiveness of a Trivalent Inactivated Influenza Vaccine in Children in Urban and Rural Kenya, 2010 to 2012.
(2016)
In Africa, recent surveillance has demonstrated a high burden of influenza, but influenza vaccine is rarely used. In Kenya, a country with a tropical climate, influenza has been shown to circulate year-round, like in other ...