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Now showing items 31-40 of 61
Trypan blue staining to determine vaginal exposure in two types of plastic vaginal applicators containing two different microbicide formulations
(2012)
Dye staining of applicators has been shown to be a reliable and objective method to test vaginal insertion in clinical microbicide trials, but different plastics, dyes, and product formulations may impact the accuracy of ...
Sexuality, HIV risk and potential acceptability of involving adolescent girls in microbicide research in Kisumu, Kenya
(University of Nairobi., 2008-12)
BACKGROUND:
Current microbicide clinical trials primarily enroll adult participants; however, females under the age of 18, because of their high rates of HIV acquisition, represent an important population for future ...
Lessons learned developing a diagnostic tool for HIV-associated dementia feasible to implement in resource-limited settings: pilot testing in Kenya
(2012)
To conduct a preliminary evaluation of the utility and reliability of a diagnostic tool for HIV-associated dementia (HAD) for use by primary health care workers (HCW) which would be feasible to implement in resource-limited ...
Single-agent tenofovir versus combination emtricitabine plus tenofovir for pre-exposure prophylaxis for HIV-1 acquisition: an update of data from a randomised, double-blind, phase 3 trial.
(2014)
Abstract
BACKGROUND:
Antiretroviral pre-exposure prophylaxis (PrEP), with daily oral tenofovir disoproxil fumarate or tenofovir disoproxil fumarate in combination with emtricitabine, has been shown to be efficacious ...
Integration of HIV Care with Primary Health Care Services: Effect on Patient Satisfaction and Stigma in Rural Kenya
(2013)
HIV departments within Kenyan health facilities are usually better staffed and equipped than departments offering non-HIV services. Integration of HIV services into primary care may address this issue of skewed resource ...
Infectious correlates of HIV-1 shedding in the female upper and lower genital tracts.
(2007)
To determine the effects of vaginal, cervical, and endometrial infections on shedding of HIV-1 RNA in the female genital tract.
Cross-sectional.
Antiretroviral-naive women from Nairobi, Kenya with CD4 cell counts ...
Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.
(2012)
BACKGROUND:
Antiretroviral preexposure prophylaxis is a promising approach for preventing human immunodeficiency virus type 1 (HIV-1) infection in heterosexual populations.
METHODS:
We conducted a randomized trial ...
Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya
(2012)
Many HIV-positive pregnant women and infants are still not receiving optimal services, preventing the goal of eliminating mother-to-child transmission (MTCT) and improving maternal child health overall. A Rapid Results ...
Bacterial vaginosis: risk factors among Kenyan women and their male partners
(Kenya Medical Research Institute, 2006)
To simultaneously examine associations of bacterial vaginosis (BV) with potential risk factors in both the female and her male partner.
We recruited women 18-45 years of age and their male partners from clinics in ...
Measurement of mucosal biomarkers in a phase 1 trial of intravaginal 3% StarPharma LTD 7013 gel (VivaGel) to assess expanded safety
(2012)
The aim of this study was to examine the effect of the 3% StarPharma LTD 7013 gel (VivaGel) on mucosal immune markers hypothesized to be associated with HIV-1 acquisition.
Phase 1, placebo-controlled, randomized, ...