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Now showing items 21-30 of 35
Improvement of vaginal health for Kenyan women at risk for acquisition of human immunodeficiency virus type 1: results of a randomized trial
(2008)
BACKGROUND:
Vaginal infections are common and have been associated with increased risk for acquisition of human immunodeficiency virus type 1 (HIV-1).
METHODS:
We conducted a randomized trial of directly observed oral ...
A prospective study of risk factors for bacterial vaginosis in HIV-1-seronegative African women
(2008)
Bacterial vaginosis (BV) is common and has been associated with increased HIV-1 susceptibility. The objective of this study was to identify risk factors for BV in African women at high risk for acquiring HIV-1.
We conducted ...
Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya
(2009-06-16)
Abstract
Access to antiretroviral therapy (ART) is increasing in resource-limited settings (RLS) and can successfully reduce HIV-related morbidity and mortality. However, virologic failure and ...
The effect of repeated half-yearly diethylcarbamazine mass treatment on wuchereria bancrofti infection and transmission in two East African communities with different levels of endemicity
(2004)
The effect of repeated half-yearly mass treatment with diethylcarbamazine (DEC, 6 mg/kg body weight)
on infection and transmission of Wuchereria bancrofti was assessed and compared in communities with high and low
endemicity ...
Relative HIV Resistance In Kenyan Sex Workers Is Not Due To An Altered Prevalence Or Mucosal Immune Impact Of Herpes Simplex Virus Type 2 Infection.
(University of Nairobi, 2009-09)
Chronic infection by herpes simplex virus type 2 (HSV-2) increases HIV susceptibility, perhaps due to HSV-2-associated increases in activated mucosal immune cells. A small number of Kenyan female sex workers (FSWs) exhibit ...
Bancroftian Filariasis Infection, Disease, And Specific Antibody Response Patterns In A High And A Low Endemicity Community In East Africa
(University of Nairobi, 2002-05)
Bancroftian filariasis infection, disease and specific antibody response patterns in a high and a low endemicity community in East Africa were analyzed and compared to assess the relationship between these parameters and ...
European and Developing Countries Clinical Trials Partnership (EDCTP): the path towards a true partnership.
(University of Nairobi., 2009-07)
BACKGROUND:
European and Developing Countries Clinical Trials Partnership (EDCTP) was founded in 2003 by the European Parliament and Council. It is a partnership of 14 European Union (EU) member states, Norway, Switzerland, ...
Evaluation of two commercially available alternatives for HIV-1 viral load testing in resource-limited settings
(2007)
There is an urgent need for low-cost assays for HIV-1 quantitation to ensure adequate follow-up of HIV-infected patients on antiretroviral
therapy (ART) in resource-limited countries. Two low-cost viral load assays are ...
Baseline morbidity in 2,990 adult African volunteers recruited to characterize laboratory reference intervals for future HIV vaccine clinical trials
(2008)
An understanding of the health of potential volunteers in Africa is essential for the safe and efficient conduct
of clinical trials, particularly for trials of preventive technologies such as vaccines that enroll healthy ...
Cervical HIV-specific IgA in a population of commercial sex workers correlates with repeated exposure but not resistance to HIV
(2009)
We conducted a comprehensive cross-sectional analysis of total and HIV-specific cervical antibody levels in HIV-
1-resistant, uninfected, and infected women in order to examine the role of HIV-specific antibody responses ...