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Now showing items 31-35 of 35
Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding
(2007)
Antiretroviral therapy (ART) may decrease HIV-1 infectivity in women by reducing genital HIV-1 shedding. To evaluate the time course and magnitude of decay in cervical and vaginal HIV-1 shedding as women initiate ART. This ...
HIV-1 RNA Dysregulates the natural TLR response to subclinical endotoxemia in Kenyan female sex-workers
(2009)
Subclinical endotoxemia has been reported in HIV-1 infected persons and may drive systemic immune
activation and pathogenesis. Proinflammatory responsiveness to endotoxin (LPS) is mediated by Toll-like receptor 4 (TLR4).
We ...
Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection
(2008)
Toll-like receptors (TLR) are important in pathogen recognition and may play a role in HIV disease. We evaluated the effect of chronic untreated and treated HIV-1 infection on systemic TLR expression and TLR signalling. ...
Associations Between Intravaginal Practices and Bacterial Vaginosis in Kenyan Female Sex Workers Without Symptoms of Vaginal Infections
(2007)
Background: Bacterial vaginosis (BV) is highly prevalent among
African women and has been associated with adverse pregnancy outcomes,
sexually transmitted diseases, and HIV-1.
Goal: The goal of this study was to analyze ...
HIV-1 acquisition and disease progression are associated with decreased high-risk sexual behaviour among Kenyan female sex workers.
(2006)
BACKGROUND:
Changes in sexual risk behaviour may occur following HIV-1 infection.
OBJECTIVE:
To test the hypothesis that HIV-1 seroconversion and disease progression are associated with changes in risk behaviours, ...