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Duodenal perforation following blunt abdominal trauma: case report.
(University of Nairobi, 1998)
A case of severe duodenal injury in a 20-year-old female due to blunt abdominal trauma secondary to road traffic accident is presented. The difficulty and hence delay in making a diagnosis of duodenal injury is discussed.
Outpatient experience with oesophageal endoscopic dilation.
(University of Nairobi, 1998)
Between March 1990 and August 1997, outpatient endoscopic balloon dilation was performed for oesophageal strictures which developed secondary to malignancies, peptic strictures, post surgical narrowing, achalasia cardia, ...
Morbidity among HIV-1-infected mothers in Kenya: prevalence and correlates of illness during 2-year postpartum follow-up.
(University of Nairobi, 2007)
Background: Much of the burden of morbidity affecting women of childbearing age in sub-Saharan Africa occurs in the context of HIV-1 infection. Understanding patterns of illness and determinants of disease in HIV-1–infected ...
Salivary Antimicrobial Peptides As Potential Biomarkers Of Periodontal Disease
(University of Nairobi, 2010-07)
Objectives: Using SELDI-TOF-MS we have previously identified putative salivary biomarkers of periodontitis. Some of these identified peaks were predicted to be antimicrobial peptides (AMPs), specifically alpha defensins ...
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression
(2012)
Recurrent somatic ASXL1 mutations occur in patients with myelodysplastic syndrome, myeloproliferative neoplasms, and acute myeloid leukemia, and are associated with adverse outcome. Despite the genetic and clinical data ...
Strategic Response To The Dynamic Economic Environment Of The Oil Marketing Companies In Kenya
(2013-03)
As recently as 10 years ago, people thought they knew most of what they needed to know
about strategy. Portfolio planning, the experience curve, Michael E. Porter’s five forces–
tools like these brought rigor and legitimacy ...
Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes
(2012)
Experimental hyperlipidemia has shown to decrease cytochrome P450 3A4 and 2C11 expression and to increase liver concentrations and the plasma protein binding of halofantrine (HF) enantiomers. The present study examined the ...
Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia
(2013)
Relapsed childhood acute lymphoblastic leukemia (ALL) carries a poor prognosis, despite intensive retreatment, owing to intrinsic drug resistance. The biological pathways that mediate resistance are unknown. Here, we report ...
Road traffic injuries in Kenya: magnitude, causes and status of intervention.
(2003)
Road traffic crashes exert a huge burden on Kenya's economy and health care services. Current interventions are sporadic, uncoordinated and ineffective. This report offers a descriptive analysis of secondary data obtained ...
An autopsy case of sudden unexplained death caused by malaria.
(University of Nairobi, 2010)
Sudden unexplained deaths, especially those unwitnessed can lead to forensic issues and would necessitate the need for a meticulous and complete postmortem examination including ancillary investigations to discover the ...