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Clinical evaluation of rosoxacin for the treatment of chancroid
(1986)
One hundred seven men with Haemophilus ducreyi-positive chancroid were assigned to receive 300 mg of rosoxacin as a single dose or 150 mg twice daily for 3 days. Ulcers and buboes were followed clinically and bacteriologicaily ...
Treatment of chancroid with ciprofloxacin. A prospective, randomized clinical trial.
(1987)
Chancroid is a major sexually transmitted disease in many developing countries. Although single-dose and short-course treatment of chancroid have been described, the increasing resistance of Hemophilus ducreyi to antimicrobial ...
Three day oral course of Augmentin to treat chancroid.
(1986)
Amoxycillin and clavulanic acid (Augmentin; Beecham Research Laboratories) was used to treat patients with bacteriologically proved chancroid in three different dose regimens. A single dose of Augmentin (amoxycillin 3 g, ...
Urethral infection with Haemophilus ducreyi in men
(1988)
Carriage of Haemophilus ducreyi has not been adequately investigated in men, and its role in urethritis is unknown. In this study 456 men with H. ducreyi-culture positive genital ulcers were investigated. Among these men, ...
Treating chancroid with enoxacin
(1988)
Increasing resistance of Haemophilus ducreyi to antimicrobials necessitates further trials of new antimicrobial agents for treating chancroid. Enoxacin has excellent in vitro activity against H ducreyi, and a randomised ...
Human immunodeficiency virus, genital ulcers and the male foreskin: synergism in HIV-1 transmission.
(1990)
Epidemiologic studies in Nairobi and elsewhere in Africa, have shown that men infected with HIV-1 more commonly have a history of genital ulcer disease compared to uninfected men. In one study, HIV infected men were three ...
A randomized, double-blind study of the efficacy of fleroxacin versus trimethoprim-sulfamethoxazole in men with culture-proven chancroid.
(World Health Organisation Centre for Research and Training on Sexually Transmitted Diseases, 1992)
Chancroid is linked to the spread of human immunodeficiency virus type 1 (HIV-1) in East Africa. Effective, easily administered therapy is a priority for the control of Haemophilus ducreyi. The efficacy of a single oral ...
Human immunodeficiency virus type 1 seroconversion in women with genital ulcers.
(1994)
Genital ulcers are implicated as a risk factor enhancing susceptibility to human immunodeficiency virus type 1 (HIV-1) infection. A prospective study to determine the incidence of and risk factors associated with acquisition ...
Cefotaxime treatment of Haemophilus ducreyi infection in Kenya.
(University of Nairobi,, 1984-12)
The authors conducted a double-blind randomized clinical trial comparing single-dose cefotaxime (1 g im) plus daily placebo injections with cefotaxime (1 g im on each of three days). Each regimen was given with probenicid ...
Single-dose therapy of gonococcal ophthalmia neonatorum with ceftriaxone
(1986)
We conducted a randomized clinical trial comparing a single intramuscular dose of 125 mg of ceftriaxone with a single intramuscular dose of 75 mg of kanamycin followed by topical gentamicin for seven days, and with a single ...