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Influence of HLA Class I Haplotypes on HIV-1 Seroconversion and Disease Progression in Pumwani Sex Worker Cohort.
(University of Nairobi, 2014-07)
We examined the effect of HLA class I haplotypes on HIV-1 seroconversion and disease progression in the Pumwani sex worker cohort. This study included 595 HIV-1 positive patients and 176 HIV negative individuals. HLA-A, ...
Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort
(2008)
OBJECTIVE:
A group of commercial sex workers in the Pumwani Sex Worker Cohort, established in 1985 in Nairobi, Kenya, remain HIV-1 uninfected despite heavy exposure to HIV-1 through active sex work. Previous studies showed ...
Full-length Hiv Type 1 Proviral Sequencing Of 10 Highly Exposed Women From Nairobi, Kenya Reveals A High Proportion Of Intersubtype Recombinants.
(University of Nairobi, 2008-06)
Phylogenetic analysis has revealed that the current HIV/AIDS pandemic consists of a multitude of different viral clades and recombinant viruses. The predominant circulating HIV-1 clade in Kenya is A1; however, Kenya borders ...
Human leukocyte antigen-DQ alleles and haplotypes and their associations with resistance and susceptibility to HIV-1 infection
(2008)
Objectives: To determine the association of DQ antigens with resistance and susceptibility
to HIV-1.
Design: Despite repeated exposure to HIV-1, a subset of women in the Pumwani Sex
Worker cohort established in Nairobi, ...