Now showing items 1-10 of 23
Human Leucocyte Antigen Supertypes And Immune Susceptibility To Hiv-1, Implications
(University of Nairobi, 2001-11-01)
Role of Sexually Transmitted Infections in Accelerated HIV-1 Disease Progression
(University of nairobi, 2000)
IL-7Ralpha expression on DC4+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation
(University of nairobi, 2006)
Many factors can influence the rate of HIV disease progression, including those that maintain T cell homeostasis. One key homeostatic regulator is the IL-7 receptor (IL-7R). Previous studies have shown IL-7R expression ...
Early HIV-1 Infection Is Associated With Reduced Frequencies of Cervical Th17 Cells.
BACKGROUND:: The hallmark of HIV infection is progressive but variable rates of systemic and mucosal CD4 depletion, leading to immunodeficiency. The impact of early HIV infection on cervical CD4 T-cell populations in ...
Human Interferon Regulatory Factor-1 Gene And Its Promoter Sequences Revealed By Population-based Complete Gene Sequencing.
(University of Nairobi, 2008-06)
Interferon regulatory factor-1 (IRF-1) plays important roles in host immunity, cell proliferation and apoptosis. The current GenBank sequence for human IRF-1 (accession number: L05072) was derived from a human placenta DNA ...
Too young to take over: - the hidden face of HIV/AIDS : orphans and vulnerable children from a Kenyan perspective
(University of Nairobi, 2004)
HIV-infected women have high numbers of CD103-CD8+ T cells residing close to the basal membrane of the ectocervical epithelium.
(University of Nairobi, 2017)
BACKGROUND: Genital mucosa is the main portal of entry for various incoming pathogens, including HIV, hence an important site for host immune defenses. Tissue-resident memory T (TRM) cells defend tissue barriers against ...