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Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate.
(University of Nairobi, 2000)
Abstract
OBJECTIVE:
To characterize functional properties of HIV-specific IgA in samples representing both systemic and mucosal compartments of HIV-1 highly exposed persistently seronegative (HEPS) individuals.
METH ...
Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 523 transcytosis across human epithelial cells.
(2000)
Abstract
HIV-1-specific IgA has been described in the genital tract and plasma of HIV-1 highly exposed, persistently seronegative (HEPS) individuals, and IgA from these sites has been shown to neutralize HIV-1. This ...
HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi
(, 2000)
Understanding how individuals with a high degree of HIV exposure avoid persistent infection is paramount to HIV vaccine design. Evidence suggests that mucosal immunity, particularly virus-specific CTL, could be critically ...