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Polymorphisms In Irf-1 Associated With Resistance To Hiv-1 Infection In Highly Exposed Uninfected Kenyan Sex Workers
(University of Nairobi, 2007-05)
OBJECTIVE:
To determine the correlation between polymorphisms in the IL-4 gene cluster and resistance to HIV-1 infection.
DESIGN:
: A cross-sectional genetic analysis of polymorphisms within the IL-4 gene cluster ...
Prevalent herpes simplex virus type 2 infection is associated with altered vaginal flora and an increased susceptibility to multiple sexually transmitted infections.
(University of Nairobi, 2007)
BACKGROUND:
Prevalent herpes simplex virus type 2 (HSV-2) infection increases human immunodeficiency virus acquisition. We hypothesized that HSV-2 infection might also predispose individuals to acquire other common ...
Plasma and mucosal fluid from HIV type 1-infected patients but not from HIV type 1-exposed uninfected subjects prevent HIV type 1-exposed DC from infecting other target cells.
(University of Nairobi, 2007-01-23)
Highly exposed persistently seronegative (HEPS) individuals have previously been shown to mount HIV-1-specific humoral and cellular immune responses in the mucosa, despite their uninfected status. It is thus possible that ...