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Genetic Diversity of Human Enterovirus 68 Strains Isolated in Kenya Using the Hypervariable 3′- End of VP1 Gene
(University of Nairobi, 2014)
Reports of increasing worldwide circulation of human enterovirus-68 (EV68) are well documented. Despite health concerns
posed by resurgence of these viruses, little is known about EV68 strains circulating in Kenya. In ...
Application of principal component analysis to multispectral-multimodal optical image analysis for malaria diagnostics.
(2014)
BACKGROUND:
Multispectral imaging microscopy is a novel microscopic technique that integrates spectroscopy with optical imaging to record both spectral and spatial information of a specimen. This enables acquisition of ...
Trends in drug resistance codons in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Kenyan parasites from 2008 to 2012
(University of Nairobi, 2014)
Background: Sulphadoxine-pyrimethamine (SP), an antifolate, was r eplaced by artemether-lumefantrine as the first-line malaria drug treatment in Kenya in 2004 due to the wide s pread of resistance. However, SP still remains ...
Phylogenetic characterization of respiratory human adenoviruses isolated from pediatrics patients in new Nyanza provincial general hospital; Kenya
(University of Nairobi, 2014)
Background: Human adenoviruses (HAdVs) are common pathogens associated with diseases affecting the respiratory tract, gastro intestinal tract as well as various organs like the liver, kidney and the brain. Currently there ...
Influenza surveillance in Kenya2006-2013: experiences and lessons learned
(University of Nairobi, 2014)
Background: Influenza sentinel surveillance at the KEMRI-National Influenza Centre (NIC) was rolled out in 2006. A team of collaborators from Kenya Medical Research Unit (KEMRI), US Army Medical research unit –Kenya ...
Molecular characterization of human coronavirus circulating in Kenya, 2009-2012
(University of Nairobi, 2014)
Background: The genome of a human coronavirus (HCoV) is composed of a linear, single-stranded, non-segmented, positive-sense RNA of 27-32 kb. The pol gene of HCoV found in ORF1ab, is a good molecular chronometer for molecular ...
Genetic polymorphisms in IL-1A and IL-1B isoforms and their associations with chronic periodontitis in the Swahili people of Kenya
(University of Nairobi, 2014)
Genetic polymorphisms in interleukin-1 (IL-1A and IL-1B) isoforms have been associated with Chronic Periodontitis (CP) in Caucasians, Asians and Arabs but little is known about their role in Africans. Therefore, this study ...
Molecular detection of enterotoxigenic escherichia coli surface antigens from patients in Machakos district hospital, Kenya
(University of Nairobi, 2014)
Introduction: Enterotoxigenic Escherichia
coli (ETEC) is known for its
public health importance globally,
however, a protective vaccine is yet
to be developed. Information regarding
the immunology of ETEC’s ...