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Flavanols from Tetrapleura tetraptera with cytotoxic activities
(University of Nairobi, 2022-05)
Tetrapleura tetraptera is a medicinal plant used in East and West Africa to treat inflammation and related diseases. From the stem bark of the plant, three previously undescribed flavan-3-ol derivatives named (2R,3S)-3,3 ...
Antibacterial Secondary Metabolites From Vernonia Auriculifera Hiern (Asteraceae) Against Mdr Phenotypes
(University of Nairobi, 2022)
Purification of the aerial parts of Vernonia auriculifera Hiern
afforded steroids (1–2), flavonoids (3–5), and polyalcohol (6).
Their structures were determined using spectral evidences as well
as by comparison with ...
Conglomeratin: a New Antibacterial Flavonol Derivative From Macaranga Conglomerata Brenan (Euphorbiaceae)
(University of Nairobi, 2022)
A new prenylated kaempferol, conglomeratin (1), alongside 7 known
compounds including flavonoids (2 and 3), ellagic acid derivatives (4
and 5), triterpenoids (6 and 7), and a coumarin (8)were isolated from
the leaves ...
Cytotoxic Alkaloids From the Root of Zanthoxylum Paracanthum (Mildbr) Kokwaro
(University of Nairobi, 2022)
Chemical investigation of the root of Zanthoxylum paracanthum afforded 1 new alkamide derivative, (2E,4E)-6-oxo-N-isobutyldeca-2,4-dienamide (1) together with 10 known congeners including one phenolic amide (2), four ...
Antiplasmodial and Antimicrobial Activities of Ent- Abietane Diterpenoids From the Roots of Suregada Zanzibariensis
(University of Nairobi, 2022)
The root extract ofSuregada zanzibariensisBaill. afforded six previ-ously describedent-abietane diterpenoids, namely 7-oxo-ent-abieta-5(6),8(14),13(15)-trien-16,12-olide (1), mangiolide (2),8,14b:11,12a-diepoxy ...
Cytotoxic Flavonoids From the Seeds of Dracaena Steudneri Engl Against Leukemia Cancer Cell Lines
(University of Nairobi, 2022)
Background: Leukemia is the most common type of childhood cancer. Numerous flavonoids isolated from plants
have been reported as potential chemotherapeutic agents against malignant growth while taking care of healthy
c ...
Laboratory and Field Performance of Metarhizium Anisopliae Isolate Icipe 41 for Sustainable Control of the Invasive Fall Armyworm Spodoptera Frugiperda (Lepidoptera: Noctuidae)
(University of Nairobi, 2022)
To overcome the negative impacts of invasive fall armyworm (FAW), this study assessed
the laboratory and field efficacy of aqueous and oil-based formulations of Metarhizium anisopliae
ICIPE 41 as an alternative source ...
Antibacterial Activities of Thirteen Naturally Occuring Compounds From Two Kenyan Medicinal Plants: Zanthoxylum Paracanthum (Mildbr) Kokwaro (Rutaceae) and Dracaena Usambarensis Engl. (Asparagaceae) Against MDR Phenotypes
(University of Nairobi, 2022)
The antibacterial potency of thirteen compounds reported from two distinct genera, Zanthoxylum (Rutaceae) and Dracaena (Asparagaceae) against a panel of sensitive and multi-drug resistant Gram-positive and Gram-negative ...
Phytochemistry and Antibacterial Potential of the Genus Garcinia
(University of Nairobi, 2022)
Species of the genus Garcinia (Clusiaceae) have been used for centuries in different
folk medicine for the treatment of several ailments, as well as food supplements.
Evidence from previous studies has demonstrated a ...
Potential Antibacterial Pharmaceuticals From the Flora of Africa
(University of Nairobi, 2022)
The present chapter highlights the antibacterial potential of nine highly active
compounds isolated from the African medicinal plants: 8,8-bis-(dihydroconiferyl)-
diferulate, buesgenine, candidone, diospyrone, ferruginin ...