Now showing items 1-4 of 4
HIV-1 persists in breast milk cells despite antiretroviral treatment to prevent mother-to-child transmission
Background: The effects of short-course antiretrovirals given to reduce mother-to-child transmission (MTCT) on temporal patterns of cell-associated HIV-1 RNA and DNA in breast milk are not well deﬁned. Methods: Women ...
Indeterminate rapid HIV-1 test results among antenatal and postnatal mothers
Summary: The sensitivity and speciﬁcity of rapid HIV-1 tests may be altered during pregnancy and postpartum. We conducted a study to determine the prevalence and correlates of false-positive Abbott DetermineTM and ...
Sensitivity and specificity of HIV rapid tests used for research and voluntary counselling and testing
Background: HIV rapid tests (RT) are a quick and non-technically demanding means to perform HIV voluntary counselling and testing (VCT) but understanding their limitations is vital to delivering quality VCT. Objective: ...
Mucosal Neisseria gonorrhoeae coinfection during HIV acquisition is associated with enhanced systemic HIV-specific CD8 T-cell responses
Background: The host immune response against mucosally acquired pathogens may be influenced by the mucosal immune milieu during acquisition. As Neisseria gonorrhoeae can impair dendritic cell and T-cell immune function, ...