Now showing items 1-4 of 4
HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers.
(University of Nairobi,, 2008-03)
OBJECTIVES: HIV-neutralizing immunoglobulin A (IgA) and HIV-specific cellular immunity have been described in highly exposed, persistently seronegative (HEPS) individuals, but well controlled studies have not been performed. ...
Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 523 transcytosis across human epithelial cells.
Abstract HIV-1-specific IgA has been described in the genital tract and plasma of HIV-1 highly exposed, persistently seronegative (HEPS) individuals, and IgA from these sites has been shown to neutralize HIV-1. This ...
Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate.
(University of Nairobi, 2000)
Abstract OBJECTIVE: To characterize functional properties of HIV-specific IgA in samples representing both systemic and mucosal compartments of HIV-1 highly exposed persistently seronegative (HEPS) individuals. METH ...
HIV-1 neutralizing activity is correlated with increased levels of chemokines in saliva of HIV-1-exposed uninfected individuals.
(University of Nairobi,, 2008)
AIM: Mucosal HIV-1 exposure stimulates a variety of mucosal immune responses, including IgA1-mediated virus neutralization, even in the absence of an established infection. We hypothesized that other immune molecules might ...