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Uptake of prevention of mother to child transmission interventions in Kenya: health systems are more influential than stigma
(2011-12-28)
Abstract
Background
We set out to determine the relative roles of stigma versus health systems in non-uptake of prevention of mother to child transmission (PMTCT) of HIV-1 interventions: we conducted cross-sectional ...
Maternal Human Leukocyte Antigen - A*2301 Is Associated with Increased Mother-to-Child HIV-1 Transmission
(2010)
We examined associations between maternal HLA and vertical HIV-1 transmission in a perinatal cohort of 277 HIV-infected women in Nairobi. HLA class I genes were amplified using sequence-specific oligonucleotide probes and ...
Latent TB detection by interferon gamma release assay (IGRA) in pregnancy predicts active TB and mortality in HIV-1 infected women and their children
(2010)
Background—We evaluated the prognostic utility of interferon-gamma release assays (IGRAs)
for active tuberculosis (TB) and mortality in Kenyan HIV-1 infected women and their infants.
Methods—Prevalence and correlates of ...
Medication diaries do not improve outcomes with highly active antiretroviral therapy in Kenyan children
(2009)
Background: As highly active antiretroviral therapy (HAART) becomes increasingly available to African children,
it is important to evaluate simple and feasible methods of improving adherence in order to maximize benefits ...
Pediatric HIV-1 in Kenya:pattern and correlates of viral load and association with mortality
(2009)
Background—There is limited information regarding the pattern and correlates of viral replication
in vertically HIV-1–infected children and its role on their outcomes in resource-limited settings.
Methods—HIV-1–infected ...
Male Antenatal Attendance and HIV Testing Are Associated with Decreased Infant HIV Infection and Increased HIV Free Survival
(2012)
Objective
To investigate the relationship between male involvement in prevention of mother-to-child HIV transmission (PMTCT) services and infant HIV acquisition and mortality a prospective cohort study was undertaken ...
Predictors of mortality in HIV-1 infected children on antiretroviral therapy in Kenya: a prospective cohort
(2010-05-18)
Abstract
Background
Among children, early mortality following highly active antiretroviral therapy (HAART) remains high. It ...
Modified vaccinia Ankara expressing HIVA antigen stimulates HIV-1-specific CD8 T cells in ELISpot assays of HIV-1 exposed infants[star]
(2005)
Recombinant modified vaccinia virus Ankara expressing HIV-1 antigens (MVA.HIVA) was used in ELISpot assays to monitor HIV-1-specific T cell responses in infants. Responses to MVA.HIVA and HIV-1 peptides were examined in ...
Breast Milk HIV-1 RNA Levels and Female Sex Are Associated With HIV-1–Specific CD8+ T-Cell Responses in HIV-1–Exposed, Uninfected Infants in Kenya
(2011)
Background. Although evidence supports a relationship between human immunodeficiency virus (HIV)–1 exposure and HIV-1−specific CD8+ T cell responses, studies have not demonstrated a direct association between the quantity ...