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Seasonal trend of Influenza in Kenya from January - October 2013
(University of Nairobi, 2014)
Background: Influenza A and B viruses cause annual epidemics of respiratory illness. The Influenza surveillance network in Kenya through its sentinel surveillance sites located throughout the country has established that ...
Origins, molecular epidemiology and genetic diversity of influenza a(H1N1)pdm09 virus in Kenya: a bayesian coalescent analysis
(University of Nairobi, 2014)
Background: An influenza pandemic caused by a swine-origin influenza virus A/H1N1 [A(H1N1)pdm09] spread worldwide in 2009 and is estimated to have caused between 151,700 and 575,400 deaths globally. The spread of influenza ...
Neuraminidase Inhibitor activities on Influenza B isolates obtained in Kenya, 2011-2012
(University of Nairobi, 2014)
Introduction: Oseltamivir and zanamivir are neuraminidase inhibitors (NAIs) with important roles as drugs for prophylaxis and treatment of influenza. Whereas there have been reports of in vivo resistance of influenza B ...
Genotypic Diversity of HRSV-A in out-patients with Acute Respiratory Infections in Kenya 2007-2010
(University of Nairobi, 2014)
Introduction: Human Respiratory Syncytial Virus is the leading viral cause of bronchiolitis and pneumonia in children and infants. Amongst adults, the elderly and the immuno-compromised are also at risk of severe RSV. RSV ...
Species and serotype diversity of human rhinoviruses from patients presenting with influenza like illness in Kenya in 2008
(University of Nairobi, 2014)
Tract infections, the main cause of the common cold and recently have been associated with more serious respiratory infections. There are over 100 known serotypes of HRV, classified into 3 species (A, B and C). In Kenya, ...
Molecular typing of respiratory human enteroviruses isolated in Kenya between 2008 -2011 using the VP1 gene
(University of Nairobi, 2014)
Background: Human enteroviruses (genus Enterovirus, family Picornaviridae) are common infectious agents grouped into HEV-A, HEV-B, HEV-C and HEV-D species. They comprise >100 serotypes and are responsible for a wide range ...
The appropriateness of WHO influenza B vaccine component to Kenya in 2011-2012
(University of Nairobi, 2014)
Background: In the 1980’s, influenza B viruses were discovered to belong to two evolutionary groupings (B/Victoria/2/87-like viruses and B/Yamagata/16/88-like viruses) that continue to co-circulate globally in the human ...