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Now showing items 41-50 of 50
Preservation HIV-1-specific IFNγ+ CD4+ T-cell responses in breakthrough infections after exposure to tenofovir gel in the CAPRISA 004 microbicide trial.
(2012-06)
The Centre for the AIDS Program of Research in South
Africa 004 trial demonstrated reduction of sexual HIV-1 acquisition
in women using a vaginal microbicide containing tenofovir. A better
understanding of the consequences ...
Breast Milk HIV-1 RNA Levels and Female Sex Are Associated With HIV-1–Specific CD8+ T-Cell Responses in HIV-1–Exposed, Uninfected Infants in Kenya
(2011)
Background. Although evidence supports a relationship between human immunodeficiency virus (HIV)–1 exposure and HIV-1−specific CD8+ T cell responses, studies have not demonstrated a direct association between the quantity ...
Evaluation of two commercially available alternatives for HIV-1 viral load testing in resource-limited settings
(2007)
There is an urgent need for low-cost assays for HIV-1 quantitation to ensure adequate follow-up of HIV-infected patients on antiretroviral
therapy (ART) in resource-limited countries. Two low-cost viral load assays are ...
Safety and Adherence to Intermittent Pre-Exposure Prophylaxis (PrEP) for HIV-1 in African Men Who Have Sex with Men and Female Sex Workers
(4/12/2012)
Background: Little is known about safety of and adherence to intermittent HIV PrEP regimens, which may be more feasible
than daily dosing in some settings. We present safety and adherence data from the first trial of an ...
Determinants of Per-Coital-Act HIV-1 Infectivity Among African HIV-1–Serodiscordant Couples
(2012)
Background. Knowledge of factors that affect per-act infectivity of human immunodeficiency virus type 1 (HIV-1) is important for designing HIV-1 prevention interventions and for the mathematical modeling of the spread of ...
No evidence for rapid subtype C spread within an epidemic in which multiple subtypes and intersubtype recombinants circulate
(2005)
There are multiple subtypes of HIV-1 circulating worldwide, but recently, subtype C has become highly prevalent, particularly in certain geographic regions. It is unclear whether the dominance of subtype C or other subtypes ...
Correlates of human herpesvirus 8 seropositivity among heterosexual men in Kenya
(2002)
Background: Several studies have suggested that sexual transmission of human
herpesvirus 8 (HHV-8) occurs among homosexual men in developed countries. However,
few studies have examined heterosexual HHV-8 transmission, ...
HIV-1 acquisition and disease progression are associated with decreased high-risk sexual behaviour among Kenyan female sex workers.
(2006)
BACKGROUND:
Changes in sexual risk behaviour may occur following HIV-1 infection.
OBJECTIVE:
To test the hypothesis that HIV-1 seroconversion and disease progression are associated with changes in risk behaviours, ...