Browsing Faculty of Agriculture & Veterinary Medicine (FAg / FVM) by Author "Zhou, Mo"
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Cloning, characterization and validation of inosine 5′-monophosphate
Cao, Shinuo; Aboge, Gabriel Oluga; Terkawi, Mohamad Alaa; Zhou, Mo; Yu, Longzheng; Luo, Yuzi; Li, Yan; Goo, Younkyoung; Kamyingkird, Ketsarin; Masatani, Tatsunori; Suzuk, Hiroshi; Igarashi, Ikuo; Yoshifumi Nishikawa; Xuenan Xuan (Department of Public Health Pharmacology and Toxicology, 2013) -
Cloning, characterization and validation of inosine 5′-monophosphate dehydrogenase of Babesia gibsoni as molecular drug target
Xuan, Xuenan; Nishikawa, Yoshifumi; Igarashi, Ikuo; Suzuki, Hiroshi; Masatani, Tatsunori; Kamyingkird, Ketsarin; Goo, Younkyoung; Li, Yan; Yu, Longzheng; Luo, Yuzi; Zhou, Mo; Terkawi, Mohamad A; Aboge, Gabriel O; Cao, Shinuo (Department of Public Health, Pharmacology and Toxicology, 2013-04)The inosine monophosphate dehydrogenase (IMPDH) enzyme has been characterized and validated as a molecular drug target in other apicomplexans but not in the genus Babesia. Subsequently, we cloned and expressed a Babesia ... -
Mycophenolic Acid, Mycophenolate Mofetil, Mizoribine, Ribavirin, and 7-Nitroindole Inhibit Propagation of Babesia Parasites by Targeting Inosine 5'-Monophosphate Dehydrogenase
Xuan, Xuenan; Nishikawa, Yoshifumi; Igarashi, Ikuo; Masatani, Tatsunori; Moumouni, Paul Franck Adjou; Kamyingkird, Ketsarin; Zhou, Mo; Terkawi, Mohamad Alaa; Aboge, Gabriel Oluga; Cao, Shinuo (2014)The resistance of Babesia parasites to current anti-babesiosis drugs is an issue of major concern. The inosine 5'-monophosphate dehydrogenase (IMPDH) of Babesia gibsoni has been identified and characterized as a molecular ... -
Prime-boost vaccination with plasmid DNA followed by recombinant vaccinia virus expressing BgGARP induced a partial protective immunity to inhibit Babesia gibsoni proliferation in dogs
Terkawi, Mohamad A; Moumouni, Paul F A; Zhou, Mo; Kamyingkird, Ketsarin; Aboge, Gabriel O; Mousa, Ahmed A; Shinuo, Cao; Xuan, Xuenan; Fukumoto, Shinya; Suzuki, Hiroshi; Masatani, Tatsunori; Yoshifumi, Nishikawa (2013)A heterologous prime-boost vaccination regime with DNA and recombinant vaccinia virus (rvv) vectors expressing relevant antigens has been shown to induce effective immune responses against several infectious pathogens. In ...