Browsing Faculty of Agriculture & Veterinary Medicine (FAg / FVM) by Subject "B. gibsoni"
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Precursors of methotrexate target dihydrofolate reductase-thymidylate synthase of Babesia gibsoni
(Department of Public Health Pharmacology and Toxicology, 2010)It is not known whether precursors of methotrexate, such as 2, 4-diamino-6-hydroxymethyl-pteridine (DAP) and 2, 4-diamino-N10-methyl-pteroic acid (DAMPA), could target the dihydrofolate reductase-thymidylate synthase ...