Browsing Faculty of Agriculture & Veterinary Medicine (FAg / FVM) by Subject "Babesia gibsoni"

Now showing items 1-6 of 6

    • Babesia gibsoni: Serodiagnosis of infection in dogs by an enzyme-linked immunosorbent assay with recombinant BgTRAP 

      Goo, Youn-Kyoung; Jia, Honglin; Aboge, G O; Terkawi, M A; Kuriki, Ken; Nakamura, Chinatsu; Kumagai, Akiko; Zhou, Lin Jin; Lee, Eung-goo; Nishikawa, Yoshifumi; Igarashi, Ikuo; Fujisaki, Kozo; Xuan, Xuenan (Department of Public Health Pharmacology and Toxicology, 2008)
      The thrombospondin-related adhesive protein of Babesia gibsoni (BgTRAPJ is known as an immunodominant antigen and is, there¬fore, considered as a candidate for the developmentof a diagnostic reagent for canine babesiosis. ...

    • Cloning, Expression, and Characterization of Babesia gibsoni Dihydrofolate Reductase-Thymidylate Synthase: Inhibitory Effect of Antifolates on Its Catalytic Activity and Parasite Proliferation 

      Aboge, Gabriel O; Terkawi, Mohamad A; Goo, Youn-Kyoung; Nishikawa, Yoshifumi; Sunaga, Fujiko; Namikawa, Kuzuhiko; Tsuji, Naotoshi; Igarashi, Ikuo; Suzuki, Hiroshi; Fujisaki, Kozo; Xuan, Xuenan (Department of Public Health Pharmacology and Toxicology, 2008)
      Dihydrofolate reductase-thymidylate synthase (DHFR-TS) is a well-validated antifolate drug target in certain pathogenic apicomplexans, but not in the genus Babesia, including Babesia gibsoni. Therefore, we isolated, cloned, ...

    • Identification of a novel B. gibsoni 27-kDa protein as a serodiagnostic antigen 

      Terkawi, M. A.; Aboge, G. Oluga; Jia, H; Goo, Y K; Ooka, H; Yamagishi, Junya; Nishikawa, Yoshifumi; Shin-ichiro, Kawazu; Fujisaki, K; Xuan, Xuenan (Department of Public Health, Pharmacology & Toxicology, University of Nairobi, 2008)
      A novel gene encoding 27-kDa protein was identified by the screening of Babesia gibsoni cDNA library with acutely infected dog serum. The BgP27 is a single copy gene with a predicted open reading frame of 762 bp and 254 ...

    • Identification of Secreted Antigen 3 from Babesia gibsoni 

      Jia, Honglin; Terkawi, M. Alaa; Aboge, Gabriel Oluga; Goo, Youn-Kyoung; Ma, Liqing; Zhou, Jinlin; Nishikawa, Yoshifumi; Igarashi, Ikuo; Fujisaki, Kozo; Xuan, Xuenan (Department of Public Health, Pharmacology and Toxicology, 2009)
      A cDNA expression library of Babesia gibsoni was screened with the serum collected from a dog experimentally infected with B. gibsoni. A novel antigen sharing homology with secreted antigen 1 of B. gibsoni was isolated. ...

    • Molecular and immunological characterization of Babesia gibsoni 

      Terkawi, M Alaa; Aboge, G; Jia, H; Goo, Y-K; Ooka, H; Yamagishi, J; Nishikawa, Y; Yokoyama, N; Igarashi, I; Kawazu, S-I; Fujisaki, K; Xuan, X (Department of Public Health, Pharmacology and Toxicology, 2009)
      Serological immune screening was used to identify a gene encoding heat shock protein-70 from Babesia gibsoni (BgHSP-70) that showed high homology with HSP-70s from other apicomplexan parasites. This gene corresponded to a ...

    • Molecularand immunological characterization of Babesia gibsoni and Babesia microti heat shockprotein-70 

      Terkawi, M A; Jia, H J; Goo, Y-K; Ooka, H; Yamagishi, J; Nishikawa, Y.; Igarashi, I; Fujisaki, K; Xuan, X (Department of Public Health Pharmacology and Toxicology, 2009)
      Serological immunoscreening was used to identify a gene encoding heat shock protein-70 from Babesia gibsoni (BgHSP-70) that showed high homology with HSP-70s from other apicomplexan parasites. This gene corresponded to ...