Browsing Faculty of Agriculture & Veterinary Medicine (FAg / FVM) by Subject "Parasite Proliferation"
Now showing items 1-1 of 1
-
Cloning, Expression, and Characterization of Babesia gibsoni Dihydrofolate Reductase-Thymidylate Synthase: Inhibitory Effect of Antifolates on Its Catalytic Activity and Parasite Proliferation
(Department of Public Health Pharmacology and Toxicology, 2008)Dihydrofolate reductase-thymidylate synthase (DHFR-TS) is a well-validated antifolate drug target in certain pathogenic apicomplexans, but not in the genus Babesia, including Babesia gibsoni. Therefore, we isolated, cloned, ...