Browsing Faculty of Science & Technology (FST) by Author "86d3f158-d213-4f49-bfdb-b55a668a419b"
Now showing items 1-4 of 4
-
Antiplasmodial and antileishmanial flavonoids from Mundulea sericea
Chepkirui, Carolyne; Ochieng, Purity J; Sarkar, Biswajyoti; Hussain, Aabid; Pal, Chiranjib; Yang, Li Jun; Coghi, Paolo; Akala, Hoseah M; Derese, Solomon; Ndakala, Albert; Heydenreich, Matthias; Wong, Vincent K W; Erdélyi, Máté; Yenesew, Abiy (University of Nairobi, 2020)Five known compounds (1-5) were isolated from the extract of Mundulea sericea leaves. Similar investigation of the roots of this plant afforded an additional three known compounds (6-8). The structures were elucidated using ... -
In Vitro Antimicrobial and Antiproliferative Activities of the Root Bark Extract and Isolated Chemical Constituents of Zanthoxylum Paracanthum Kokwaro (Rutaceae)
Kaigongi, Magrate M; Lukhoba, Catherine W; Yaouba, Souaibou; Makunga, Nokwanda P; Githiomi, Joseph; Yenesew, Abiy (University of Nairobi, 2020)Abstract: Zanthoxylum paracanthum Kokwaro (Rutaceae) is an endemic Kenyan and Tanzanian plant used in folk medicine by local populations. Although other Zanthoxylum species have been studied, only Z. paracantum stem ... -
A new C-C linked benzophenathridine-2-quinoline dimer, and the antiplasmodial activity of alkaloids from Zanthoxylum holstzianum
Akampurira, Denis; Akala, Hoseah M; Derese, Solomon; Heydenreich, Matthias; Yenesew, Abiy (University of Nairobi, 2023)The CH2Cl2/MeOH (1:1) extract of Zanthoxylum holstzianum stem bark showed good antiplasmodial activity (IC50 2.5 ± 0.3 and 2.6 ± 0.3 µg/mL against the W2 and D6 strains of Plasmodium falciparum, respectively). From the ... -
A new β-hydroxydihydrochalcone from Tephrosia uniflora, and the revision of three β-hydroxydihydrochalcones to flavanones
Chepkirui, Carolyne; Bourgard, Catarina; Gilissen, Pieter J; Ndakala, Albert; Derese, Solomon; Gütlin, Yukino; Erdélyi, Máté; Yenesew, Abiy (University of Nairobi, 2022-04)The CH2Cl2/MeOH (1:1) extract of the stems of Tephrosia uniflora yielded the new β-hydroxydihydrochalcone (S)-elatadihydrochalcone-2'-methyl ether (1) along with the three known compounds elongatin (2), (S)-elatadihydrochalcone ...