Browsing Faculty of Science & Technology (FST) by Author "b044bdde-d156-488b-81fb-058b84dd6408"
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Antimalarial pyrido[1,2-a]benzimidazoles: lead optimization, parasite life cycle stage profile, mechanistic evaluation, killing kinetics, and in vivo oral efficacy in a mouse model.
Kawaljit, Singh; Okombo, John; Christel, Brunschwig; Ndubi, Ferdinand; Linley, Barnard; Chad, Wilkinson; Njogu, Peter M.; Njoroge, Mathew; Lizahn, Laing; Marta, Machado; Miguel, Prudêncio; Janette, Reader; Mariette, Botha; Sindisiwe, Nondaba; Lyn-Marie, Birkholtz; Sonja, Lauterbach; Alisje, Churchyard; Coetzer, Theresa L.; Burrows, Jeremy N.; Clive, Yeates; Paolo, Denti; Lubbe, Wiesner; Egan, Timothy J.; Sergio, Wittlin; Kelly, Chibale (University of Nairobi, 2017)Further structure-activity relationship (SAR) studies on the recently identified pyrido[1,2-a]benzimidazole (PBI) antimalarials have led to the identification of potent, metabolically stable compounds with improved in vivo ...