Browsing Faculty of Science & Technology (FST) by Author "Taboada, Rosa"
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Directed Ring-Opening of 1,5-Dioxaspiro[3.2]hexanes: Selective Formation of 2,2-Disubstituted Oxetanes
Taboada, Rosa; Ordonio, Grace G; Ndakala, Albert J; Howell, Amy R (Department of Chemistry, University of Nairobi, 2003)1,5-Dioxaspiro[3.2]hexanes undergo ring-opening reactions with many heteroatom nucleophiles to provide α-substituted-β‘-hydroxy ketones. However, certain Lewis acidic nucleophiles provide 2,2-disubstituted oxetanes. Herein, ...