Browsing Faculty of Science & Technology (FST) by Author "Yan, Guiyun"
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Behavioral Responses of Pyrethroid Resistant and Susceptible Anopheles Gambiae Mosquitoes to Insecticide Treated Bed Net
Machani, Maxwell G; Ochomo, Eric; Amimo, Fred; Mukabana, Wolfgang R; Githeko, Andrew K; Yan, Guiyun; Afrane, Yaw A (University of Nairobi, 2022)Background Long-lasting insecticidal nets are an effective tool in reducing malaria transmission. However, with increasing insecticide resistance little is known about how physiologically resistant malaria vectors behave ... -
Rare Alleles and Signatures of Selection on the Immunodominant Domains of Pfs230 and Pfs48/45 in Malaria Parasites From Western Kenya
Ochwedo, Kevin O; Ariri, Fredrick O; Otambo, Wilfred O; Magomere, Edwin O; Debrah, Isaiah; Onyango, Shirley A; Orondo, Pauline W; Atieli, Harrysone E; Ogolla, Sidney O; Otieno, Antony C. A; Mukabana, Wolfgang R; Githeko, Andrew K; Lee, Ming-Chieh; Yan, Guiyun; Zhong, Daibin; Kazura, James W (University of Nairobi, 2022)Background: Malaria elimination and eradication efforts can be advanced by including transmission-blocking or reducing vaccines (TBVs) alongside existing interventions. Key transmission-blocking vaccine candidates, such ... -
Signatures of selection and drivers for novel mutation on transmission-blocking vaccine candidate Pfs25 gene in western Kenya
Ochwedo, Kevin O; Onyango, Shirley A; Omondi, Collince J; Orondo, Pauline W; Ondeto, Benyl M; Lee, Ming-Chieh; Atieli, Harrysone E; Ogolla, Sidney O; Githeko, Andrew K; Otieno, Antony C A; Mukabana, Wolfgang R; Yan, Guiyun; Zhong, Daibin; Kazura, James W (University of Nairobi, 2022-04)Background: Leading transmission-blocking vaccine candidates such as Plasmodium falciparum surface protein 25 (Pfs25 gene) may undergo antigenic alterations which may render them ineffective or allele-specific. This study ... -
Topography and malaria transmission heterogeneity in western Kenya highlands: prospects for focal vector control
Githeko, Andrew K; Ayisi, John M; Odada, Peter K; Francis, Atieli; Ndenga, Bryson A; Githure, John I; Yan, Guiyun (College of Physical and Biological Sciences, 2006)Background Recent resurgence of malaria in the highlands of Western Kenya has called for a more comprehensive understanding of the previously neglected complex highland vector ecology. Besides other drivers of malaria ...