Browsing Faculty of Science & Technology (FST) by Author "Zhong, Daibin"

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    • Rare Alleles and Signatures of Selection on the Immunodominant Domains of Pfs230 and Pfs48/45 in Malaria Parasites From Western Kenya 

      Ochwedo, Kevin O; Ariri, Fredrick O; Otambo, Wilfred O; Magomere, Edwin O; Debrah, Isaiah; Onyango, Shirley A; Orondo, Pauline W; Atieli, Harrysone E; Ogolla, Sidney O; Otieno, Antony C. A; Mukabana, Wolfgang R; Githeko, Andrew K; Lee, Ming-Chieh; Yan, Guiyun; Zhong, Daibin; Kazura, James W (University of Nairobi, 2022)
      Background: Malaria elimination and eradication efforts can be advanced by including transmission-blocking or reducing vaccines (TBVs) alongside existing interventions. Key transmission-blocking vaccine candidates, such ...

    • Signatures of selection and drivers for novel mutation on transmission-blocking vaccine candidate Pfs25 gene in western Kenya 

      Ochwedo, Kevin O; Onyango, Shirley A; Omondi, Collince J; Orondo, Pauline W; Ondeto, Benyl M; Lee, Ming-Chieh; Atieli, Harrysone E; Ogolla, Sidney O; Githeko, Andrew K; Otieno, Antony C A; Mukabana, Wolfgang R; Yan, Guiyun; Zhong, Daibin; Kazura, James W (University of Nairobi, 2022-04)
      Background: Leading transmission-blocking vaccine candidates such as Plasmodium falciparum surface protein 25 (Pfs25 gene) may undergo antigenic alterations which may render them ineffective or allele-specific. This study ...