Browsing Faculty of Science & Technology (FST) by Subject "Malaria; Plasmodium berghei; Drug resistance; Cross-resistance; Lumefantrine; Piperaquine"

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    • Plasmodium berghei ANKA: Selection of resistance to piperaquine and lumefantrine in a mouse model 

      Kiboi, D M; Irungu, B N; Langat, B; Wittlin, S; Brun, R; Chollet, J; Abiodun, O; Nganga, J K; Nyambati, V C S; Rukunga, G M; Bell, A; Nzila, A (University of Nairobi, 2009)
      We have selected piperaquine (PQ) and lumefantrine (LM) resistant Plasmodium berghei ANKA parasite lines in mice by drug pressure. Effective doses that reduce parasitaemia by 90% (ED90) of PQ and LM against the parent line ...