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SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination.
(University of Nairobi, 2015)
Aberrant elevation of JARID1B and histone H3 lysine 4 trimethylation (H3K4me3) is frequently observed in many diseases including prostate cancer (PCa), yet the mechanisms on the regulation of JARID1B and H3K4me3 through ...