Search
Now showing items 1-2 of 2
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression
(2012)
Recurrent somatic ASXL1 mutations occur in patients with myelodysplastic syndrome, myeloproliferative neoplasms, and acute myeloid leukemia, and are associated with adverse outcome. Despite the genetic and clinical data ...
The role of mutations in epigenetic regulators in myeloid malignancies
(2012)
The role of mutations in epigenetic regulators in myeloid malignancies.
Recent genomic studies have identified novel recurrent somatic mutations in patients with myeloid malignancies, including myeloproliferative ...