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In vivo screening of antimalarial activity of Acacia mellifera (Benth) (Leguminosae) on Plasmodium berghei in mice.
(2007)
The activities of total extracts and lupane triterpenes, isolated from the stem bark of Acacia mellifera, were evaluated against Plasmodium berghei strain ANKA in a female Swiss mouse model. Five isolated compounds and the ...
Cytotoxic lupane-type triterpenoids from Acacia mellifera.
(2004)
One new and eight previously described lupane-type metabolites were isolated for the first time from Acacia mellifera (Leguminosae). Based on spectral analyses, the structure of the new compound was elucidated as ...
Antimicrobial activity of pentacyclic triterpenes isolated from Acacia mellifera
(2008)
Acacia mellifera has been used widely in traditional African medicines against various diseases. Among the Kipsigis community of Kenya, water extracts from the plant is used for the treatment of skin diseases, coughs and ...
High-throughput screening and sensitized bacteria identify an M. tuberculosis dihydrofolate reductase inhibitor with whole cell activity.
(2012)
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is a bacterial pathogen that claims roughly 1.4 million lives every year. Current drug regimens are inefficient at clearing infection, requiring at ...
Antimicrobial activity of Acacia mellifera extracts and lupane triterpenes.
(2009)
ETHNOPHARMACOLOGICAL RELEVANCE:
Acacia mellifera (Vahl) Benth (Leguminosae) is a subtropical medicinal plant that is widely used in traditional African medicines against various diseases such as pneumonia and malaria.
AIM ...
Lupane triterpenoids from Acacia mellifera with cytotoxic activity.
(2007)
Three new pentacyclic triterpenoids: (20R)-3-oxolupan-30-al (1), (20S)-3-oxolupan-30-al (2) and (20R)-28-hydroxylupen-30-al-3-one (3), along with (20S)-3beta-hydroxylupan-30-al (4), the latter previously described as a ...
Antiplasmodial potential of traditional antimalarial phytotherapy remedies used by the Kwale community of the Kenyan Coast.
(University of Nairobi, 2015-05-20)
ETHNOPHARMACOLOGICAL RELEVANCE:
In Kenya, 22 million people are at risk of malaria, 70% of them are in rural areas and most of these people use traditional plant based medicines to treat malaria. The aim of the study ...
Phytochemical constituents of some medicinal plants used by the Nandis of South Nandi district, Kenya
(2011)
Alkaloids, saponins, anthraquinones, glycosides, phenolics, terpenoids and flavonoids
distribution in ten medicinal plants belonging to different families were assessed and
compared. The medicinal plants investigated ...
Propagation of some endangered indigenous trees from the South Nandi District of Kenya using cheap, non-mist technology
(2008)
Vegetative propagation studies were carried out at Maseno University, Kenya in the year 2004 and 2005 using stem cuttings on three endangered indigenous tree species namely Asystasia schimperi, carissa edulis and Toddalia ...