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A new β-hydroxydihydrochalcone from Tephrosia uniflora, and the revision of three β-hydroxydihydrochalcones to flavanones
(University of Nairobi, 2022-04)
The CH2Cl2/MeOH (1:1) extract of the stems of Tephrosia uniflora yielded the new β-hydroxydihydrochalcone (S)-elatadihydrochalcone-2'-methyl ether (1) along with the three known compounds elongatin (2), (S)-elatadihydrochalcone ...
Cytotoxic Flavonoids From the Seeds of Dracaena Steudneri Engl Against Leukemia Cancer Cell Lines
(University of Nairobi, 2022)
Background: Leukemia is the most common type of childhood cancer. Numerous flavonoids isolated from plants
have been reported as potential chemotherapeutic agents against malignant growth while taking care of healthy
c ...
Benzo[ b]naphtho[2,1- d]furans and 2-Phenylnaphthalenes from Streblus usambarensis
(University of Nairobi, 2023)
Three new benzo[b]naphtho[2,1-d]furans, usambarins A-C (1-3), five new 2-phenylnaphthalenes, usambarins D-H (4-8), a new flavan (9), and a new phenyl-1-benzoxepin (10) as well as two known compounds (11 and 12) were isolated ...
A new C-C linked benzophenathridine-2-quinoline dimer, and the antiplasmodial activity of alkaloids from Zanthoxylum holstzianum
(University of Nairobi, 2023)
The CH2Cl2/MeOH (1:1) extract of Zanthoxylum holstzianum stem bark showed good antiplasmodial activity (IC50 2.5 ± 0.3 and 2.6 ± 0.3 µg/mL against the W2 and D6 strains of Plasmodium falciparum, respectively). From the ...
Benzo[ b]naphtho[2,1- d]furans and 2-Phenylnaphthalenes from Streblus usambarensis
(University of Nairobi, 2023)
Three new benzo[b]naphtho[2,1-d]furans, usambarins A-C (1-3), five new 2-phenylnaphthalenes, usambarins D-H (4-8), a new flavan (9), and a new phenyl-1-benzoxepin (10) as well as two known compounds (11 and 12) were isolated ...