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Antibacterial activity and structure-activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes
(University of Nairobi, 2016)
In the current study forty eight compounds belonging to anthraquinones, naphthoquinones, benzoquinones, flavonoids (chalcones and polymethoxylated flavones) and diterpenoids (clerodanes and kauranes) were explored for their ...
The Chemistry of African Croton species
(University of Nairobi, 2016)
The genus Croton is one of the largest of Euphorbiaceae sensu stricto, and consists of over 1300 species of trees, shrubs and herbs that are distributed worldwide in the warm tropics and subtropics. It is reported that 124 ...
Diterpenoids from the roots of Croton dichogamus Pax.
(University of Nairobi, 2017-12)
Four previously undescribed diterpenoids including two crotofolanes, crotodichogamoin A and B, and two halimanes, crothalimene A and B, a new sesquiterpenoid, and fifteen previously reported compounds, including the ...
Cytotoxicity of Plumbagin, Rapanone and 12 other naturally occurring Quinones from Kenyan Flora towards human carcinoma cells.
(University of Nairobi, 2016)
BACKGROUND:
Cancer is a major public health concern globally and chemotherapy remains the principal mode of the treatment of various malignant diseases.
METHODS:
This study was designed to investigate the cytotoxicity ...
Isolation of a new β-carboline alkaloid from aerial parts of Triclisia sacleuxii and its antibacterial and cytotoxicity effects.
(University of Nairobi, 2017)
A new β-carboline alkaloid named sacleuximine A (1) together with known compounds palmatine (2), isotetrandrine (3), trans-N-feruloyltyramine (4), trans-N-caffeoyltyramine (5), yangambin (6), syringaresinol (7), sesamin ...